Any model · Your biology · Your lab

The virtual AI lab for drug discovery.

Turn your biology into a frontier discovery system, on any model. Rank the candidates worth a program and compound every result into an edge that stays yours. Built for target ID and biomarker discovery.

Benchmark

Frontier target ID performance. With any model.

Harnesses that reach the frontier on any model and improve with every result, grounded in therapeutically relevant evaluation.

DESeq2 baseline
1.9
Reasoning Models
7.54.0× DESeq2
Co-Scientists
8.34.4× DESeq2
Helical Harness + Reasoning Models
14.47.7× DESeq2
BEST

Recovery@100 vs. Open Targets top-5% evidence, averaged across 7 indications. Reasoning Models = avg of Codex + Kimi K2.7. Higher is better.

Click here to see the full benchmark

How it works

Build your own frontier virtual lab.
Target ID & Biomarker Discovery.

01

Bio Foundation Models, tuned to your biology.

Align Bio Foundation Models to your data and experiments at scale to surface novel biology with real therapeutic value.

02

Orchestrate your models into ranked candidates.

Helical's best-in-class harnesses combine your tuned models, leading tools and scientific evidence into defensible, mechanistically grounded shortlists.

03

Measure what actually moves your biology.

Helical's therapeutically relevant benchmark scores every harness, model and candidate, so the system keeps and builds on what works.

04

Improve the system with every result.

Your wet-lab result and scientist decision compound into your edge. Improve your system, not a frontier model's.

Trusted by

Trusted by the world's leading biopharma R&D teams.

03

More of the world's top-20 pharma

Under NDA

The Sovereign Lab

Enterprise readiness by design.

SOC 2 TYPE II (in progress)

No lock-in, no data leakage.

Swap reasoning models on performance or preference whenever a better one lands, and your data never reaches a model provider.

Scientists build it with you.

Deployed Science Engineers partner with your team to build frontier AI systems on your data and your indications.

A full stack, not a tool.

Bio FM post-training, orchestration, evaluation and deployment come as one stack, so you swap any model and deploy how you need.

The virtual AI lab for biology.